TypeScript is a statically-typed superset of JavaScript that requires transpilation and traditionally pairs with runtimes like Node.js, while Bun is a modern all-in-one JavaScript runtime and toolkit built with Zig that executes TypeScript natively. This comparison addresses a common misconception: TypeScript is a language/type system, whereas Bun is a runtime environment—they operate at different layers, but the practical question developers face is whether to use Node.js + TypeScript tooling or switch to Bun's integrated approach.
This matters because Bun fundamentally changes the TypeScript development experience by eliminating build steps and providing a unified toolkit (runtime, bundler, package manager, test runner), while Node.js + TypeScript offers the most mature ecosystem with proven stability. Teams choosing between traditional TypeScript workflows (tsc, ts-node, esbuild) and Bun's zero-config execution need to weigh raw performance and developer experience against ecosystem maturity and enterprise readiness.
For new projects prioritizing performance and developer velocity—especially microservices, APIs, or real-time applications—Bun is the clear winner in 2025. Its native TypeScript execution eliminates build complexity while delivering 5-10x faster runtime performance, and the all-in-one toolkit reduces toolchain fragmentation significantly. Teams comfortable with a rapidly evolving runtime and modern greenfield architectures should default to Bun, particularly when using frameworks like Elysia, Hono, or Fastify that leverage its speed advantages.
However, Node.js with TypeScript remains the safer choice for enterprise environments, large existing codebases, or projects requiring maximum ecosystem compatibility and stability. If your application depends on specific native modules, requires long-term support guarantees, or involves complex integrations with legacy systems, the maturity of Node.js + TypeScript outweighs Bun's performance gains. For teams that cannot tolerate potential breaking changes or need the broadest possible npm package compatibility, stick with the proven Node.js toolchain despite its slower execution and more complex configuration.