DOMPurify and xss (also known as js-xss) are both JavaScript libraries designed to sanitize HTML and prevent cross-site scripting (XSS) attacks. DOMPurify, developed by security firm Cure53, uses the browser's native DOM parser to sanitize content, while xss takes a pattern-matching approach with a whitelist-based filtering system. Both libraries aim to make user-generated content safe for display in web applications, but they differ significantly in their implementation philosophy and runtime environments.
This comparison is relevant for developers building applications that handle untrusted HTML input—from rich text editors and comment systems to email renderers and markdown parsers. DOMPurify primarily targets browser environments (with jsdom support for Node.js), making it ideal for client-side sanitization, while xss was designed with Node.js as a first-class citizen and works seamlessly in both server and browser contexts. Frontend developers working with React, Vue, or Angular will likely encounter DOMPurify, while backend Node.js developers often reach for xss.
For browser-based applications where security is paramount, DOMPurify is the clear choice. Its DOM-based approach provides superior protection against sophisticated XSS attacks, including mutation XSS vectors that regex-based solutions miss. The larger bundle size is a worthwhile tradeoff for applications handling untrusted rich content, and the extensive configuration options make it adaptable to complex requirements. If you're building a modern single-page application with React, Vue, or Angular, DOMPurify's browser-first design and security pedigree make it the industry standard.
Choose xss for Node.js backend applications, API servers, or situations where bundle size is critical. Its native Node.js support without jsdom dependencies makes it architecturally cleaner for server-side rendering and email generation workflows. The smaller footprint (less than half of DOMPurify when gzipped) matters for edge computing environments or applications with strict performance budgets. While less robust against novel attack vectors, xss provides adequate protection for most use cases when you're sanitizing on the server before storage, especially when combined with Content Security Policy headers.